Substrate: Nitric-oxide synthase, brain (Enzyme: Synthetase)
Seq-ID: P29475 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
MINT-3999982   VAC14_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
arginine binding,
heme binding,
cadmium ion binding,
NADP or NADPH binding,
FAD binding,
calmodulin binding,
nitric-oxide synthase activity,
tetrahydrobiopterin binding,
FMN binding		 sarcolemma,
sarcoplasmic reticulum,
dendritic spine,
cytoskeleton,
photoreceptor inner segment,
perinuclear region of cytoplasm		 positive regulation of vasodilation,
neurotransmitter biosynthetic process,
myoblast fusion,
oxidation reduction,
response to hypoxia,
response to heat,
arginine catabolic process,
negative regulation of calcium ion transport into cytosol,
multicellular organismal response to stress,
regulation of cardiac muscle contraction,
nitric oxide biosynthetic process
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 852 ERKSYKVRFNSVSSYSDSQKS CaM-KII_alpha 10400690
LTP
0.33
 - Flavodoxin_1
0.37
 - medium
S 852 ERKSYKVRFNSVSSYSDSQKS CaM-KII_alpha 10874031
LTP
0.33
 - Flavodoxin_1
0.37
 - medium
S 852 ERKSYKVRFNSVSSYSDSQKS CaM-KII_alpha 12630910
LTP
0.33
 - Flavodoxin_1
0.37
 - medium
S 1417 YEVTNRLRSESIAFIEESKKD - 11052978
LTP
0.19
 - -
0.38
 - medium

Substrate: Nitric-oxide synthase, brain (Enzyme: Synthetase)
Seq-ID: P29476 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):
MINT-58323   AT2B4_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
amino acid binding,
protein homodimerization activity,
heme binding,
cadmium ion binding,
enzyme binding,
NADP or NADPH binding,
FAD binding,
calmodulin binding,
nitric-oxide synthase activity,
FMN binding		 dendritic spine,
cytosol,
nuclear membrane,
synapse,
photoreceptor inner segment,
mitochondrial outer membrane,
azurophil granule,
perinuclear region of cytoplasm,
sarcolemma		 response to organic nitrogen,
negative regulation of blood pressure,
response to vitamin E,
oxidation reduction,
response to hypoxia,
response to estrogen stimulus,
response to organic cyclic substance,
aging,
response to heat,
arginine catabolic process,
negative regulation of insulin secretion,
nitric oxide biosynthetic process,
negative regulation of heart contraction,
regulation of sensory perception of pain,
response to ethanol,
positive regulation of vasodilation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 374 QYYSSIKRFGSKAHMDRLEEV PKA_group 1721813
LTP
1.00
 - NO_synthase
0.32
 1OM4 25.41%
S 847 ERKSYKVRFNSVSSYSDSRKS RSK_group 16984226
LTP
1.00
 - Flavodoxin_1
0.36
 1TLL 45.90%

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